Anti Mullerian Hormone (AMH) is an indicator of ovarian functional reserve

Under the influence of the AMH formed in the Sertoli cells, the Mullerian ducts degenerate in male fetuses. This leads to the normal development of the male genitals. Female fetuses do not have AMH, and so develop the internal female genital organs. In women, at the onset of puberty AMH, like inhibin B, is formed by the granulosa cells of the maturing ovarian follicle, but not by the primordial follicles and also not by the antral follicles under direct FSH regulation in the final stage of follicular growth. AMH is the biological regulator of folliculogenesis and of primordial follicular rupture. It reduces the rate of follicle conversion from the primordial to the growing stage and regulates follicle growth by inhibiting FSH-induced conversion from the early to the late stage (Fig. 1) [1].